The measurement of urea in the blood is done via Blood urea nitrogen test or simply referred to as BUN.Ĭreatinine, on the other hand, is a molecular protein produced by the muscle and is relatively freely filtered by the kidneys. As the peptide bond breakage creates nitrogenous waste products, ammonia is produced which is converted into a nontoxic waste called urea by the liver. These are then absorbed through the gut and are the building blocks for protein. Normally, when we eat protein, the peptide bond gets broken to yield amino acids. One of such biomarker sets is that of the BUN: Creatinine ratio. ![]() However, when you consider this objectively to define how much a person is dehydrated, some laboratory biomarkers can help. For the most part, dehydration is a clinical diagnosis, from signs and symptoms that signify loss of water and electrolytes from the body. One of the many incomplete tasks in the hydration space is using biomarkers to objectively identify dehydration. Any derangement in the values signifies the impaired kidney function.The BUN : Creatinine ratio: Understanding Biomarkers of Hydration and Kidney Function. The normal value of creatinine in urine is found 500 to 2000 mg/day and may vary with age. Creatinine is filtered by the kidneys and excreted in urine. Urine creatinine: This test measures the amount of creatinine in urine. If the GFR is high then it may indicate chances of kidney failure. The normal value in males is 97 to 137 mL/min and females is 88 to 128mL/min. It is also done to estimate the glomerular filtration rate (GFR). Creatinine is the waste product released when the muscle is put to work. Creatinine levels may be decreased slightly in pregnancy.Ĭreatinine clearance: This test determines the kidney functioning and suggests kidney dysfunction or decreased blood flow to kidneys as in congestive heart failure. If the level of creatinine is more than the normal value it indicates kidney conditions such as glomerulonephritis, pyelonephritis, acute tubular necrosis, kidney stones, prostate disease, and complications of diabetes. Normal value of creatinine is 0.8 – 1.4mg/dL Females have low creatinine than males because of the muscle mass. Creatinine is filtered from blood and excreted in urine by the kidneys. Creatinine is a byproduct of creatine produced when muscles are put to use. Decreased concentration of BUN is not common and may occur in cases of malnutrition and severe kidney disease.īlood Creatinine: This test measures the amount of creatinine in blood which signifies the filtering capability of kidneys. Elevated levels suggest impaired kidney function such as acute or chronic kidney disease, decreased blood flow to kidneys as in congestive heart failure and shock. ![]() The normal values of nitrogen in blood urea ranges from 7 to 20mg/dL. Urea is a waste product released from degradation of protein, which is filtered in the blood and excreted in urine by kidneys. Some of the commonly conducted laboratory tests areīlood urea nitrogen (BUN): The BUN test measures the nitrogen content in blood urea. These tests reveal the functioning and abnormalities, if any. Kidney function tests are the tests performed to evaluate kidney functioning. Kidney :: Prostate :: Urinary Bladder :: Testes Home » Patient Info » Genito Urinary System » Kidney » Kidney Function tests
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